New studies on the effect of grapefruit juice on medication has found it can interact with many drugs, sometimes with dangerous consequences.
Drinking the juice with medication can change the way the drug works in the body.
Researchers have learned that the fruit temporarily knocks out an enzyme in the intestine, an effect that can last for 24 hours after consumption. Certain drugs get into the body through this enzyme.
Once grapefruit is added to the mix, the drug isn't metabolized and seeps through the gut and into the bloodstream.
"You don't have to worry about that with most drugs. Most drugs have a big margin of safety," says researcher David Spence.
"You could take ten times the dose of penicillin and it would be very unlikely to cause trouble. But for some drugs, there's a narrow margin of safety. A narrow difference between an effective dose and a toxic dose."
Can affect blood pressure, kidneys
Those drugs include ones that lower blood pressure. Blended with grapefruit jucie, the drugs can force your blood pressure to go too low. The heart beats too quickly, you might feel weak and even collapse.
In severe cases, grapefruit, in combination with drugs used to lower cholesterol, can lead to kidney problems.
The allergy medication, Seldane, combined with grapefruit juice, is especially dangerous. At least one death is blamed on the combination. Seldane is no longer available in Canada.
The known list of drugs that interact with grapefruit juice is growing. Pharmacists are instructed to warn their clients of the dangers. Spence says that's not enough.
Found this online along with several others, Thanks Mark, many men here including me take medication and mine is one that if increased potency is happening that is not good. I dont like grapefruit but you got me curious.
Standing together is so much better than hiding in the dark.
***I am a three time WoR Retreat Alumni*** The Round Table
, Men's CSA Group, Monday 7:30pm CST, MaleSurvivor Chat